Are Infants ‘born with allergies’?
Are Infants ‘born with allergies’? Dr Sheri Tenpenny presents.
• IgG levels in the term infant are similar to maternal levels as due to transplacental transfer.
• However, no other class of immunoglobulin passes the placental barrier, including IgE.
• Therefore, infants develop IgE in response to an external stimuli.
• Elevated levels of IgE antibodies are associated with atopic/hypersensitivity diseases such as allergies, asthma, and eczema.
– Some children with atopic diseases have plasma IgE antibody levels 5 to 20 times than normal.
Could it be Latex?
• Package Insert Warming:
“The stopper to the vial of this product contains dry natural latex rubber that may cause allergic reactions.”
– Many vaccines have latex listed as part of the vaccine
– By 6 months, infants may have received as many a 19 injections and 19 potential exposures to latex
Nut Allergies …is it the Latex?
• Peanuts are a legume (in the same family as peas and lentils) and have proteins are similar in structure to those in tree nuts.
• People who are allergic to tree nuts, such as almonds, Brazil nuts, walnuts, hazelnuts, macadamias, pistachios, pecans, and cashews can also be allergic to peanuts.
• A study from France found that 8% of babies 4 months of age had IgE antibodies to peanut allergies.
Pediatric Allergy & Immunology. 10(1):14-20, February 1999
• A study from England found that 80% of children with peanut allergy reacted to their first known exposure to foods. This suggests that they have been previously sensitized containing peanut
Clinical & Experimental Allergy 27 (11) , 1240–1246
No published research investigating the connection between vaccine latex and peanut allergy.
• Latex shares IgE epitopes with grasses and weed pollens, specifically mugwort, ragweed, timothy grass, and birch. These plants, common in temperate zones, produce a great deal of pollen.
• Children who react violently to pollen may have an underlying latex allergy.
• Food allergies account for 30,000 visits to the emergency room each year.
• Latex has been documented to cross-react with papaya, mango, avocado, banana, chestnut, passion fruit, fig, melon, kiwi, pineapple, peach, tomato, grape, pear, apple, orange, chestnut, and almond.
• Because legumes are also derived from plants there can occasionally be cross-reactivity between fruits and vegetables and legumes.
Vaccines, Gelatin, Asthma-Allergies
• Gelatin has been shown to cause allergic reactions and asthma in many children
– Ann Allergy Asthma Immunol. 2000 Mar;84(3):341-4.
• There is a strong relationship between serious allergic reactions, including anaphylaxis, to vaccines and the presence of specific IgE to gelatin.
– J Allergy Clin Immunol 1996;98.'1058-61.
• Children known to be allergic to gelatin should not receive the chickenpox vaccine.
– Vaccine 17 (1999) 327-329.
• Vaccines that contain gelatin:
– Varivax (children), Zostrix (adults)
– Tripedia (DTaP--babies), Boostrix (DTaP--teens)
– MMR, Fluzone , Yellow fever
– ProQuad (MMR + Chickenpox)