Study Questions Rotavirus Vaccine in India
Prevention of Rotavirus Diarrhea in India:
Is Vaccination the Only Strategy?
RAKESH LODHA AND DHEERAJ SHAH
The rotavirus serotypes prevalent in the country appear to be different from that in the west. In a multicenter study enrolling 4243 children with diarrhea (39% tested positive for rotavirus), the most common types of
strains were G2P(4) (25.7% of strains), G1P(8) (22.1%), and G9P(8) (8.5%) . The authors of the study observed that 22.1% of the strains identified in this study would be covered by Rotarix (GSK Biologicals) and 47.9% by RotaTeq (Merck) . While there is some evidence to suggest that there may be cross-protection, the same has not been shown in India.